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Condition

Coronary Artery Disease (CAD)

Cholesterol plaque narrowing the arteries that feed the heart muscle.

Heart with multiple coronary plaques
Cholesterol plaque builds up silently — long before the first symptom.

What it is

Coronary Artery Disease is the slow build-up of cholesterol plaque inside the heart's arteries. As the arteries narrow, the heart muscle gets less blood — especially during exertion — causing chest discomfort (angina) or breathlessness.

Symptoms

Man with chest tightness while climbing stairs
Discomfort that comes with exertion and eases with rest is the classic clue.
  • Chest tightness or pressure on walking, climbing stairs, or stress
  • Pain relieved by rest within minutes
  • Breathlessness with mild exertion
  • Sometimes only fatigue (especially in women and diabetics)

Risk factors

  • Diabetes
  • Hypertension
  • Smoking
  • High cholesterol
  • Family history
  • Abdominal obesity
  • Chronic stress

How it's diagnosed

Treadmill stress test in a cardiology clinic
A stress test shows how the heart behaves when it has to work hard.
  • ECG
  • Stress test (TMT or stress echo)
  • Echocardiography
  • CT coronary angiography
  • Coronary angiography

Treatment options

Coronary stent on balloon catheter beside cardiac medicines
Some blockages need medicines, some need a stent — the right answer depends on you.
  • Medical therapy: statins, aspirin, beta-blocker, nitrates, ACE inhibitor
  • Angioplasty with drug-eluting stent for significant blockages
  • Bypass surgery (CABG) for multi-vessel or left main disease in selected cases
  • Aggressive risk-factor control

Prevention

  • Annual check-up after age 35 if you have any risk factor
  • Keep LDL cholesterol below 70 mg/dL if you already have CAD
  • HbA1c below 7% for diabetics
  • BP below 130/80
  • Daily exercise and Mediterranean-style diet

Related procedures

FAQ

Questions patients ask us most

Can blockages be reversed without surgery?+

Mild to moderate blockages can sometimes regress with intense lifestyle change and high-dose statin. But significant blockages causing symptoms usually need angioplasty or bypass.

What is the difference between angiography and angioplasty?+

Angiography is a test that finds blockages. Angioplasty is the treatment that opens them.

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